Women and girls with epilepsy (WOGE) especially those living in Low and Middle-income countries (LMICs) are confronted daily by a myriad of challenges that significantly reduces their quality of life.  These women and girls with epilepsy have very low access to educational and employment opportunities, are often excluded from social activities, are more likely to divorce, lose their jobs, and are less likely to get married. They’re more vulnerable to sexual exploitation and rape which increase their risks of contracting sexually transmitted diseases, unwanted pregnancies, and becoming single parents. Women and Girls with Epilepsy Empowerment Project (WOGEEP) is a community-based women empowerment project for WOGE. This project entails leadership in community engagement initiatives, social mobilization, and advocacy; partnership and collaboration to; teach job skills and seed businesses; Create a safe space where WOGE can gather with other women and talk about issues like gender equity, women’s rights, or health; training on health care, family planning, domestic violence, and reproductive rights; build social networks through which WOGE can have more support and greater opportunities to effect change in their communities; provide leadership training for WOGE to increase their presence in the public sphere. The proposed project will not only empower these women and girls, improve their quality of life but will be a platform to contribute towards the achievement of SDG 5 targets in communities in Cameroon, Sub-Saharan Africa, and globally.